The Anatomy & Physiology section of the HESI A2 covers 11 body systems, hundreds of structures, and countless physiological processes. Trying to memorize it all through repetition alone is overwhelming — and inefficient. Mnemonics (memory devices) can cut your study time dramatically by converting complex information into memorable phrases, acronyms, and mental images.
This guide provides battle-tested mnemonics for the highest-yield anatomy topics on the HESI A2, organized by body system. Bookmark this page and use these tricks alongside your regular study sessions.
How Mnemonics Work (And Why They're So Effective)
Your brain remembers information better when it's:
- Organized — grouped into logical chunks instead of isolated facts
- Visual — connected to a mental image
- Emotional/Funny — unusual or humorous content sticks
- Associated — linked to something you already know
Mnemonics exploit all four of these principles. A silly sentence is easier to remember than a list of 12 cranial nerves — and once you remember the sentence, you can decode the list.
💡 Study Tip: Mnemonics work best when you create your own. The ones in this guide are proven starters, but personalizing them (using your name, favorite foods, or inside jokes) makes them even stickier.
Skeletal System Mnemonics
Cranial Bones (8 bones)
Mnemonic: "PEST OF 6"
- Parietal (2)
- Ethmoid (1)
- Sphenoid (1)
- Temporal (2)
- Occipital (1)
- Frontal (1)
- = 6 types, 8 total bones
Carpal Bones (8 bones of the wrist)
Mnemonic: "Some Lovers Try Positions That They Can't Handle"
- Scaphoid → Lunate → Triquetrum → Pisiform (proximal row)
- Trapezium → Trapezoid → Capitate → Hamate (distal row)
Tarsal Bones (7 bones of the ankle)
Mnemonic: "Tiger Cubs Need MILC"
- Talus → Calcaneus → Navicular → Medial cuneiform → Intermediate cuneiform → Lateral cuneiform → Cuboid
Layers of Bone (outside to inside)
Mnemonic: "People Can Smell Bone"
- Periosteum → Compact bone → Spongy bone → Bone marrow
Muscular System Mnemonics
Rotator Cuff Muscles (4 muscles)
Mnemonic: "SITS"
- Supraspinatus
- Infraspinatus
- Teres minor
- Subscapularis
Muscle Action Terms
Remember contrasting pairs:
- Flexion/Extension — "Flex to bring closer, extend to stretch away"
- Abduction/Adduction — "Ab-duct = away (like being abducted from home), Ad-duct = add to the body (bring closer)"
- Pronation/Supination — "Supination = you can hold a bowl of soup palm up; Pronation = pour it out"
Cardiovascular System Mnemonics
Blood Flow Through the Heart
Mnemonic: "Tri Before You Bi"
Blood passes through the tricuspid valve before the bicuspid (mitral) valve.
Full flow: Vena Cava → Right Atrium → Tricuspid valve → Right Ventricle → Pulmonary valve → Pulmonary Arteries → Lungs → Pulmonary Veins → Left Atrium → Bicuspid/Mitral valve → Left Ventricle → Aortic valve → Aorta → Body
Arteries vs. Veins
Mnemonic: "Arteries Away, Veins inVade"
- Arteries carry blood Away from the heart
- Veins carry blood back (inVade) to the heart
Remember: Pulmonary Vessels Are the Exception
Mnemonic: "Pulmonary vessels are the rebels"
- Pulmonary arteries carry deoxygenated blood (opposite of other arteries)
- Pulmonary veins carry oxygenated blood (opposite of other veins)
Heart Valves (in order)
Mnemonic: "Try Pulling My Aorta"
- Tricuspid → Pulmonary → Mitral → Aortic
Blood Types & Compatibility
Universal Donor: O- (think: "Offers to everyone")
Universal Recipient: AB+ (think: "AB accepts All Blood")
Respiratory System Mnemonics
Airway Order (from outside in)
Mnemonic: "Never Let Monkeys Eat Bananas"
- Nose/Mouth → Larynx → Pharynx (okay, the M is for the pharynx — just remember the sequence!) → Actually, a better one:
Better Mnemonic: "Please Leave The Breathing Alone"
- Pharynx → Larynx → Trachea → Bronchi → Alveoli
Inhalation vs. Exhalation
Mnemonic: "Diaphragm Down = Draw in air"
- Inhalation: Diaphragm contracts (moves DOWN), chest expands, air rushes IN
- Exhalation: Diaphragm relaxes (moves UP), chest compresses, air pushed OUT
Gas Exchange
Think: "O₂ In, CO₂ Out" at the alveoli. Oxygen diffuses from alveoli → blood. Carbon dioxide diffuses from blood → alveoli. Both move from high to low concentration (passive diffusion).
Nervous System Mnemonics
12 Cranial Nerves
Mnemonic: "Oh, Oh, Oh, To Touch And Feel Very Good Velvet, AH!"
- Olfactory
- Optic
- Oculomotor
- Trochlear
- Trigeminal
- Abducens
- Facial
- Vestibulocochlear
- Glossopharyngeal
- Vagus
- Accessory (Spinal Accessory)
- Hypoglossal
Sensory vs. Motor vs. Both
Mnemonic: "Some Say Marry Money, But My Brother Says Big Brains Matter More"
- Sensory, Sensory, Motor, Motor, Both, Motor, Both, Sensory, Both, Both, Motor, Motor
Sympathetic vs. Parasympathetic
Mnemonic: "Fight or Flight vs. Rest and Digest"
- Sympathetic: Fight or flight — increases heart rate, dilates pupils, diverts blood to muscles
- Parasympathetic: Rest and digest — slows heart rate, constricts pupils, promotes digestion
Brain Lobes & Functions
Mnemonic: "Frontal = Forward thinking, Parietal = Perception, Temporal = Time (hearing/memory), Occipital = Optic (vision)"
Digestive System Mnemonics
Order of the GI Tract
Mnemonic: "Mother Eats Peanut Butter Standing Down Low In Convenience (stores) Right Around Christmas"
- Mouth → Esophagus → Pharynx (actually pharynx comes before esophagus — better version below)
Simplified: "My Plate Empties Slowly, Digesting Junk Isn't Cool, Right? Always Careful."
- Mouth → Pharynx → Esophagus → Stomach → Duodenum → Jejunum → Ileum → Cecum → Rectum → Anus (with the Colon surrounding the small intestine)
Small Intestine Sections
Mnemonic: "DJ I" (like a DJ)
- Duodenum (shortest, receives bile/pancreatic juices) → Jejunum (middle, most absorption) → Ileum (longest, absorbs B12 & bile salts)
Accessory Organs
Remember: "Liver, Gallbladder, Pancreas" — "LiGaP helps digestion"
- Liver produces bile
- Gallbladder stores bile
- Pancreas produces digestive enzymes + bicarbonate
Endocrine System Mnemonics
Major Endocrine Glands (Top to Bottom)
Mnemonic: "Happy People Party Till After Party" (head to groin)
- Hypothalamus → Pituitary → Parathyroid/Thyroid → Adrenals → Pancreas (islets) → Gonads
Thyroid vs. Parathyroid
Think opposites:
- Calcitonin (thyroid) = tones down calcium (lowers blood calcium → stores in bones)
- PTH (parathyroid) = pulls calcium from bones (raises blood calcium)
Memory trick: "Calci-TONE-in TONES calcium DOWN"
Insulin vs. Glucagon
Both from the pancreas, opposite effects:
- Insulin — "Insulin lets glucose IN to cells" → lowers blood sugar
- Glucagon — "Glucagon makes Glucose GO up" → raises blood sugar
Urinary System Mnemonics
Urine Formation Steps
Mnemonic: "Filter, Reabsorb, Secrete" = FRS = "Friendly Renal System"
- Filtration (glomerulus → Bowman's capsule)
- Reabsorption (tubules → blood — keeps the good stuff)
- Secretion (blood → tubules — dumps the bad stuff)
Kidney Structure (outer to inner)
Mnemonic: "Come, Meditate, and Pee"
- Cortex (outer) → Medulla (middle) → Pelvis (inner, collects urine)
Nephron Parts
The nephron is the functional unit of the kidney. Remember the flow: Glomerulus → Bowman's Capsule → Proximal Convoluted Tubule → Loop of Henle → Distal Convoluted Tubule → Collecting Duct
Mnemonic: "Go Bring Peace, Love, Donuts, Cookies"
Immune/Lymphatic System Mnemonics
Types of White Blood Cells
Mnemonic: "Never Let Monkeys Eat Bananas"
- Neutrophils (most common, 60-70%, first responders)
- Lymphocytes (B-cells and T-cells, adaptive immunity)
- Monocytes (become macrophages, "big eaters")
- Eosinophils (fight parasites and allergies)
- Basophils (least common, release histamine)
Count order (most to least): Neutrophils > Lymphocytes > Monocytes > Eosinophils > Basophils
Antibody Types (Immunoglobulins)
Mnemonic: "GAMED"
- IgG — most abundant, crosses placenta (75% of antibodies)
- IgA — found in secretions (saliva, tears, breast milk)
- IgM — first responder, largest antibody
- IgE — allergic reactions and parasites
- IgD — found on B-cell surfaces, least understood
Quick-Reference Mnemonic Cheat Sheet
| Topic | Mnemonic | What It Encodes |
|---|---|---|
| Cranial bones | PEST OF 6 | Parietal, Ethmoid, Sphenoid, Temporal, Occipital, Frontal |
| Carpal bones | Some Lovers Try Positions… | 8 wrist bones in order |
| Rotator cuff | SITS | 4 rotator cuff muscles |
| Heart valves | Try Pulling My Aorta | Tricuspid, Pulmonary, Mitral, Aortic |
| Airway path | Please Leave The Breathing Alone | Pharynx, Larynx, Trachea, Bronchi, Alveoli |
| Cranial nerves | Oh Oh Oh To Touch And Feel… | 12 cranial nerves in order |
| Small intestine | DJ I | Duodenum, Jejunum, Ileum |
| Urine formation | Friendly Renal System (FRS) | Filtration, Reabsorption, Secretion |
| WBC types | Never Let Monkeys Eat Bananas | Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils |
| Antibodies | GAMED | IgG, IgA, IgM, IgE, IgD |
How to Study with Mnemonics Effectively
- Learn the mnemonic AND the content — mnemonics are retrieval cues, not replacements for understanding
- Practice decoding — cover the answer and see if you can reconstruct the list from the mnemonic alone
- Use spaced repetition — review mnemonics at increasing intervals (day 1, day 3, day 7, day 14)
- Combine with flashcards — put the mnemonic on one side and the full decoded list on the other
- Create your own — personal mnemonics using names, places, or experiences you know are the stickiest
- Test yourself — active recall beats passive review every time
🧠 Pair Mnemonics with Active Practice
Our 400+ flashcards cover every body system tested on the HESI A2 — perfect for reinforcing mnemonics with active recall. Plus, our practice exams test these exact concepts in exam-style questions so you know your mnemonics actually translate to correct answers.
Key Takeaways
- Mnemonics convert complex lists into memorable phrases — they exploit how your brain naturally stores information
- The most high-yield systems for the HESI A2 are cardiovascular, nervous, skeletal, and digestive
- Personalize mnemonics for maximum retention — the funnier or more personal, the better
- Always pair mnemonics with understanding — know why the list matters, not just the list itself
- Use spaced repetition and active recall to lock mnemonics into long-term memory
- Practice with exam-style questions to confirm your mnemonics translate to correct answers on test day